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Árvai I., Rosdy B., Fogarasi A., Birinyi P.: Pharmaceutical development in prehospital therapy for epileptic patients
Generalized epileptic seizures without immediate therapy can have fatal consequences (brain damage, death), and therefore prehospital care is a lifesaver that can be performed by relatives. Until now, apart from rectal diazepam, there was no other preparation for prehospital rescue in Hungary. In adolescence, the use of a suppository emergency is socially difficult to accept. Therefore, we aimed to develop a more modern, more effective and socially acceptable new product at Mikszáth Pharmacy. The midazolam solution was chosen which is well absorbed by buccal and nasal administration. Injection into the nose is done with the MAD drug spraying system developed for this purpose, and the solution is applied to the oral mucosa in the buccal form. To sum up, we have achieved a significant quality leap in the treatment of epileptic patients with our newly introduced life-saving medicine, which has also been authorized by the authorities.